HCPCS Level II · Drugs administered other than oral
J0131: Injection, acetaminophen, not otherwise specified,10 mg
J0131 is the HCPCS Level II code for Injection, acetaminophen, not otherwise specified,10 mg. Section J, Drugs administered other than oral. Section-level billing guidance applies.
About this code
Inj, acetaminophen (nos).
J0131 is a HCPCS Level II code in section J (Drugs administered other than oral). The full official descriptor is: Injection, acetaminophen, not otherwise specified,10 mg.
J-codes cover drugs administered other than oral (injectable, infused, intravenous). Document the drug name, NDC (National Drug Code), dose administered, units billed, route, and site. Wastage if applicable (JW modifier for single-dose vials).
Payer-specific coverage rules vary. Always cross-check against the current Medicare Local Coverage Determination (LCD) for the adjudicating Medicare Administrative Contractor (MAC) or the commercial-payer policy.
Billing context
What practitioners watch for on J0131.
Section-level billing guidance for drugs administered other than oral. Code-specific notes ship as the dataset matures.
Documentation
J-codes cover drugs administered other than oral (injectable, infused, intravenous). Document the drug name, NDC (National Drug Code), dose administered, units billed, route, and site. Wastage if applicable (JW modifier for single-dose vials).
Common denial categories
- CO-16: Information missing or incorrect on the claim or supporting documentation. Add documentation specificity (NDC for drugs, serial number for DME, mileage for transport) and resubmit.
- CO-50: Service not deemed medically necessary. Confirm the diagnosis-procedure relationship matches the payer LCD/NCD; attach clinical justification and resubmit.
- CO-151: Payer benefit maximum reached for this period (often DME rental cycles). Verify benefit history; for DME rental-to-purchase cycles confirm month count and switch billing to purchase code where applicable.
Coverage signal
Drug coverage typically requires NDC and units. Self-administered drugs are usually patient pharmacy benefit, not medical benefit. Buy-and-bill drugs (J-codes) are billed on the medical claim with average sales price (ASP) reimbursement.
Common specialties
Oncology · Rheumatology · Infectious Disease · Internal Medicine
Companion codes
Codes commonly billed alongside J0131 based on Medonix client production data and CMS coding guidance.
- 96365IV infusion, therapeutic, first hourCPT
- 96374IV push, single drugCPT
- 96413Chemotherapy, IV infusion, first hourCPT
CPT is a registered trademark of the American Medical Association. Codes shown for educational reference only.
Sources
Where this entry comes from.
- NLM Clinical Tables Search Service: the official U.S. National Library of Medicine API for HCPCS Level II lookup.
- CMS HCPCS Quarterly Update: the authoritative HCPCS Level II release with annual major updates each January.
- CMS Medicare Coverage Database: Local Coverage Determinations and National Coverage Determinations for payer-specific rules.
Frequently asked
About HCPCS code J0131.
Talk to RCM
Ready to recover every dollar your practice earns?
See your projected revenue lift in 60 seconds, or talk to a senior RCM strategist now. No commitment. Same-day slots available.
- 30-day parallel-run guarantee
- Targets written into the contract
- HIPAA · SOC 2 Type II · HITRUST
